Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length189 amino acids

Chemical FormulaC938H1493N261O251S8

DescriptionStandard

        PAALPMVHEPMLLLAVTEFVANSAAFTYFTAGALRRNISDDTLPRRFPLQLRTKSLGLFSPQLQERYPDQPMELQLWARRQPLISCRPDALHGTLFGSAEAFVVLPNATRVPVLLLNIDANVTGKPSISGNRLRGTVRLMGGGPALRAPCPAQGLPVLQVTRLETLLKFGLWLFGVPWANSECCPHPVP
    

Molecular Weight20699.01 Da

Isoelectric Point (pI)9.69

Net Charge (pH 7.0)6.20

Net Charge (pH 7.4) 5.91

Charge Density (pH 7.0) 0.0328

GRAVY Index0.10

Hydrophobic Moment 0.57

Boman Index0.11

Instability Index62.15

Aliphatic Index 99.63

Aromaticity 0.0741

Extinction Coeff. Reduced 19480.00

Extinction Coeff. Oxidized 19730.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8023.31

LogP -92.74

H-bond Donors 277.0

H-bond Acceptors 268.0

Rotatable Bonds 649.0

Heavy Atoms 1458.0

Ring Count 41.0

Amide Bonds 203.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0346701 VERIFIED: NO

Provenance & Taxonomy

OrganismAlopecoenas beccarii [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria