Peptide Database

Peptide NameLantibiotic

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Standard StatusStandard

Sequence Length47 amino acids

Chemical FormulaC205H329N61O76S5

DescriptionStandard

        MEKVLDLDVQVKANNNSNDSSGDERITSHSLCTPGCAKTGSFNSFCC
    

Molecular Weight5024.49 Da

Isoelectric Point (pI)4.89

Net Charge (pH 7.0)-2.44

Net Charge (pH 7.4) -2.78

Charge Density (pH 7.0) -0.0520

GRAVY Index-0.47

Hydrophobic Moment 0.40

Boman Index-0.08

Instability Index19.09

Aliphatic Index 55.96

Aromaticity 0.0426

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 250.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2246.41

LogP -33.78

H-bond Donors 80.0

H-bond Acceptors 80.0

Rotatable Bonds 169.0

Heavy Atoms 347.0

Ring Count 4.0

Amide Bonds 52.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0221868 VERIFIED: NO

Provenance & Taxonomy

OrganismStaphylococcus argenteus [Bacterium]

FamilyLantibiotic

Structure & Mods

Configthioether-cyclized lantibiotic scaffold [Cyclic]

Chiralitypost-translationally modified ribosomal peptide [Modified]

Other ModsLanthionine/methyllanthionine-type thioether crosslinks are implied by the lantibiotic annotation

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive

TargetGram-positive bacteria