Peptide Database

Peptide NamePN285

Function Ontology

Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide

Delivery / Targeting ▸ Drug delivery vehicle

Standard StatusStandard

Sequence Length12 amino acids

Chemical FormulaC65H103N23O23

DescriptionStandard

        FKQQQQQQQQQQ
    

Molecular Weight1574.65 Da

Isoelectric Point (pI)8.75

Net Charge (pH 7.0)0.76

Net Charge (pH 7.4) 0.55

Charge Density (pH 7.0) 0.0633

GRAVY Index-3.01

Hydrophobic Moment 0.19

Boman Index-0.73

Instability Index160.79

Aliphatic Index 0.00

Aromaticity 0.0833

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 840.34

LogP -12.24

H-bond Donors 24.0

H-bond Acceptors 24.0

Rotatable Bonds 59.0

Heavy Atoms 111.0

Ring Count 1.0

Amide Bonds 21.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0060182 VERIFIED: NO

Provenance & Taxonomy

OrganismSynthetic construct [Synthetic]

FamilySynthetic CPP

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitymixed L/D amino-acid peptide [Mixed]

N-TermMaleimide labeling

C-TermAmidation

Other ModsN-term detail: Maleimide; lowercase source residues at positions 4,6,8,10,12 denote stereochemical modification

Bio-Activity Profile

Function

Cell-penetrating peptide

Target9 L/LacZ cells

MethodCellular uptake assay

RECORD: Rec_0286949 VERIFIED: NO

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyPN285

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitymixed L/D amino-acid peptide [Mixed]

N-TermMaleimide addition

C-TermAmidation

Bio-Activity Profile

Function

Cell-penetrating peptide Cargo delivery