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MYP_112390
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Basic Information
Shepherin I
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
28 amino acids
C95H124N44O30
Standard
Sequence
GYGGHGGHGGHGGHGGHGGHGHGGGGHG
Physicochemical Analysis
2362.28 Da
7.28
0.46
-0.15
0.0163
-1.23
0.17
0.22
13.61
0.00
0.0357
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1098.69
-20.84
38.0
38.0
73.0
169.0
9.0
27.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0038119 VERIFIED: YES
Provenance & Taxonomy
Capsella bursa-pastoris [Plant]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Erwinia herbicola
PMID11117262 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11117262/
RECORD: Rec_0042542 VERIFIED: YES
Provenance & Taxonomy
Capsella bursa-pastoris [Plant]
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Amidation
allo-residue reported
Bio-Activity Profile
Antimicrobial Antifungal
C. parapsilosis ATCC 22019
6.25 μM
MIC
PaperCharacterization and cDNA cloning of two glycine- and histidine-rich antimicrobial peptides from the roots of shepherd's purse, Capsella bursa-pastoris.
RECORD: Rec_0047531 VERIFIED: YES
Provenance & Taxonomy
Capsella bursa-pastoris [Animal]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative Antifungal
Cryptococcus neoformans
2.5 μg/mL
IC50
PaperPubMed PMID: 11117262 PMID11117262 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11117262/
RECORD: Rec_0049281 VERIFIED: YES
Provenance & Taxonomy
Capsella bursa pastoris [Plant]
Shepherin family
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Hemolytic Anti-Gram-negative
Serratia sp
8 μg/mL
IC50
PaperPubMed PMID 11117262 | PubMed PMID 25106500 PMID11117262;25106500 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11117262/
RECORD: Rec_0056541 VERIFIED: YES
Provenance & Taxonomy
Capsella bursa-pastoris [Animal]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative Antifungal
Salmonella typhimurium
2.5 μg/mL
IC50
PaperPubMed PMID: 11117262 PMID11117262 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11117262/
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