Peptide Database

Peptide NameBactericidal permeability-increasing protein

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length218 amino acids

Chemical FormulaC1112H1747N273O309S5

DescriptionStandard

        MGFTYKLTFLFFMAAFVGAVDKEKPDFAGIFKQKGLDNFLKEGVSLLQKQLYQIQLPEFSGSQKFGFLGSAKYKLYSLALKKVELPNYQVSPLPNSGLKLSISGVLIDVDGRWEVRFGFIHEDGTFNIKVKGLSISVGLILGKDGSGKPTISLSECSAHISNVEVHMSGTIGWLVELFHNKVESELKTLLENKICPEITQAINTQLLPLLQNLPGGIF
    

Molecular Weight24044.73 Da

Isoelectric Point (pI)8.42

Net Charge (pH 7.0)1.85

Net Charge (pH 7.4) 1.34

Charge Density (pH 7.0) 0.0085

GRAVY Index0.12

Hydrophobic Moment 0.64

Boman Index0.17

Instability Index32.68

Aliphatic Index 104.59

Aromaticity 0.1055

Extinction Coeff. Reduced 18450.00

Extinction Coeff. Oxidized 18575.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0371696 VERIFIED: NO

Provenance & Taxonomy

OrganismXenopus laevis [Animal]

Tax ID8355

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxic Non-hemolytic Non-ribosomal

TargetGram-negative bacteria

MethodQualitative functional evidence