Peptide Database

Peptide NamegB122R4A

Function Ontology

Antimicrobial

Antiviral

Antiviral ▸ Anti-Herpesvirus ▸ Anti-HSV

Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition

Standard StatusStandard

Sequence Length15 amino acids

Chemical FormulaC86H108N20O20

DescriptionStandard

        GHRAYFTFGGGYVYF
    

Molecular Weight1741.90 Da

Isoelectric Point (pI)8.50

Net Charge (pH 7.0)0.84

Net Charge (pH 7.4) 0.59

Charge Density (pH 7.0) 0.0563

GRAVY Index0.03

Hydrophobic Moment 0.31

Boman Index0.33

Instability Index23.33

Aliphatic Index 26.00

Aromaticity 0.4000

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 642.22

LogP -3.43

H-bond Donors 24.0

H-bond Acceptors 22.0

Rotatable Bonds 49.0

Heavy Atoms 126.0

Ring Count 7.0

Amide Bonds 14.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0172746 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Antiviral

TargetHerpes simplex virus type 1(HSV-1):comprehensive antiviral activity

Activity26.4±13.5 μM

MethodEC50

RECORD: Rec_0274075 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Antiviral

RECORD: Rec_0381518 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyProtein-derived synthetic peptide

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antiviral Anti-HSV Entry inhibition

TargetHerpes simplex virus type 1 (HSV-1)

Activity26.4±13.5 μM

MethodEC50

Half-LifeMammalian: 30 h; Yeast: >20 h; E. coli: >10 h

PaperMultiple peptides homologous to herpes simplex virus type 1 glycoprotein B inhibit viral infection. | Akkarawongsa R, Pocaro NE, Case G, Kolb AW, Brandt CR. | Antimicrob Agents Chemother. 2009 Mar;53(3):987-96. | DOI:10.1128/AAC.00793-08 | PMID:19104014 PMID19104014 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19104014/