Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length107 amino acids

Chemical FormulaC512H815N135O155S4

DescriptionStandard

        LSFFSPFSLSCSRIHVTAVELPSASISLLPGSGIKLVIGNASLTIDMNWSIRTWMYKDNGRGTVHVSKVFVTAIFSTPLDNTGPTSISFTSCRTTSGDVDIKLNGKT
    

Molecular Weight11470.02 Da

Isoelectric Point (pI)9.19

Net Charge (pH 7.0)2.92

Net Charge (pH 7.4) 2.57

Charge Density (pH 7.0) 0.0273

GRAVY Index0.21

Hydrophobic Moment 0.52

Boman Index0.16

Instability Index16.99

Aliphatic Index 91.03

Aromaticity 0.0841

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12615.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4616.76

LogP -53.57

H-bond Donors 167.0

H-bond Acceptors 164.0

Rotatable Bonds 370.0

Heavy Atoms 806.0

Ring Count 18.0

Amide Bonds 111.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0207922 VERIFIED: NO

Provenance & Taxonomy

OrganismToxostoma redivivum [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria