Peptide Database

Peptide NameH6

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length6 amino acids

Chemical FormulaC36H74N16O7

DescriptionStandard

        KRKKRK
    

Molecular Weight843.08 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)5.76

Net Charge (pH 7.4) 5.55

Charge Density (pH 7.0) 0.9594

GRAVY Index-4.10

Hydrophobic Moment 0.58

Boman Index-1.84

Instability Index117.00

Aliphatic Index 0.00

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 436.70

LogP -4.14

H-bond Donors 17.0

H-bond Acceptors 13.0

Rotatable Bonds 35.0

Heavy Atoms 59.0

Ring Count 0.0

Amide Bonds 5.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0402483 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetEscherichia coli DH5alpha

Activity64 μM

MethodMIC

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