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MYP_112205
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Basic Information
P2
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
20 amino acids
C107H191N45O27
Standard
Sequence
TTSIRRRYQVSLIRRHRGKR
Physicochemical Analysis
2539.95 Da
12.00
7.48
7.24
0.3742
-1.49
0.52
-0.76
105.32
73.00
0.0500
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1248.46
-15.07
50.0
36.0
89.0
179.0
2.0
20.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0219027 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli NDM
4 μM
MBC
PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/
RECORD: Rec_0310947 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Acinetobacter baumannii 5075
2 μM
MBC
PaperDiscovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/
RECORD: Rec_0339174 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Pseudomonas aeruginosa 14
2 μM
MBC
PaperDiscovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/
RECORD: Rec_0352639 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
human red blood cells
50 μM
Hemolysis
PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/
RECORD: Rec_0378293 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Pseudomonas aeruginosa strain PA14
PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/
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