Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length68 amino acids

Chemical FormulaC372H593N109O85S9

DescriptionStandard

        MRIHYLLFFFFFLFLVPAPGKMGWLLERINNMYCKVRQGRCRFIRCTSKEENIGTCSLGRRKCCRKKK
    

Molecular Weight8240.95 Da

Isoelectric Point (pI)10.32

Net Charge (pH 7.0)12.53

Net Charge (pH 7.4) 12.16

Charge Density (pH 7.0) 0.1842

GRAVY Index-0.18

Hydrophobic Moment 0.63

Boman Index-0.12

Instability Index60.98

Aliphatic Index 73.09

Aromaticity 0.1471

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3184.79

LogP -22.48

H-bond Donors 122.0

H-bond Acceptors 108.0

Rotatable Bonds 280.0

Heavy Atoms 575.0

Ring Count 14.0

Amide Bonds 71.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0052157 VERIFIED: NO

Provenance & Taxonomy

OrganismMonodelphis domestica [Bacterium]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defensin Non-hemolytic Non-ribosomal