Peptide Database

Peptide NameHNH endonuclease

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Nuclease

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length115 amino acids

Chemical FormulaC582H908N164O170S2

DescriptionStandard

        MSVTNNGEGAKIPSNIADKLRGRHYDSFRKSREDLWLEISKDPELSKQFSNGNIEAMQEGKAPTAPFAGHYVGPKQVIKKFEIHHIKPIEEGGGVYDIDNLRITTPKLHKFIHYG
    

Molecular Weight12986.56 Da

Isoelectric Point (pI)8.83

Net Charge (pH 7.0)2.04

Net Charge (pH 7.4) 1.48

Charge Density (pH 7.0) 0.0177

GRAVY Index-0.74

Hydrophobic Moment 0.64

Boman Index-0.08

Instability Index69.69

Aliphatic Index 72.96

Aromaticity 0.0870

Extinction Coeff. Reduced 11460.00

Extinction Coeff. Oxidized 11460.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5379.56

LogP -51.27

H-bond Donors 182.0

H-bond Acceptors 180.0

Rotatable Bonds 437.0

Heavy Atoms 918.0

Ring Count 24.0

Amide Bonds 123.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0138527 VERIFIED: NO

Provenance & Taxonomy

OrganismSalmonella [Bacterium]

FamilyPyocin/Colicin

Tax ID590

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Endonuclease Hydrolase Nuclease Non-hemolytic Non-ribosomal