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MYP_112068
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Basic Information
Temporin-SHd
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antiparasitic ▸ Anti-Leishmania ▸ Antileishmanial
Antiparasitic ▸ Antiprotozoal
Antiparasitic ▸ Antiprotozoal ▸ Anti-Trypanosoma
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Venom / Toxin ▸ General toxin ▸ Toxicity
Standard
17 amino acids
C82H132N18O18
Standard
Sequence
FLPAALAGIGGILGKLF
Physicochemical Analysis
1658.03 Da
8.75
0.76
0.55
0.0447
1.65
0.36
0.69
30.68
155.29
0.1176
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
546.15
-0.86
18.0
19.0
52.0
118.0
3.0
16.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0193655 VERIFIED: YES
Provenance & Taxonomy
Pelophylax saharicus [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal Antifungal
Leishmania infantum MHOM/MA/67/ITMAP-263
6.7 μM
IC50
PMID23116712 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23116712/
RECORD: Rec_0209077 VERIFIED: YES
Provenance & Taxonomy
Pelophylax saharica [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antiparasitic
S. enteritidis
>200 μM
MIC
PaperTemporin-SHf, a new type of phe-rich and hydrophobic ultrashort antimicrobial peptide
RECORD: Rec_0211959 VERIFIED: YES
Provenance & Taxonomy
Pelophylax saharicus [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal Antifungal
Leishmania tropica MHOM/SU/74/SAF-K27
13.9 μM
IC50
PMID23116712 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23116712/
RECORD: Rec_0212060 VERIFIED: YES
Provenance & Taxonomy
Pelophylax saharicus [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal Antifungal
Staphylococcus aureus ATCC 25923
6.25 μM
MIC
PMID23116712 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23116712/
RECORD: Rec_0227701 VERIFIED: YES
Provenance & Taxonomy
Pelophylax saharicus [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal Antifungal
Leishmania infantum MHOM/MA/67/ITMAP-263
23.5 μM
IC50
PMID23116712 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23116712/
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