Peptide Database

Peptide NameUnnamed

Function Ontology

Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Enzyme modulation ▸ Enzyme inhibition ▸ Amylase inhibition ▸ Alpha-amylase inhibitory

Enzyme modulation ▸ Enzyme inhibition ▸ COX-1 Inhibitory

Enzyme modulation ▸ Enzyme inhibition ▸ COX-2 Inhibitory

Enzyme modulation ▸ Enzyme inhibition ▸ Lipase inhibition

Enzyme modulation ▸ Enzyme inhibition ▸ Lipoxygenase Inhibitory

Immunology ▸ Inflammation modulation ▸ Anti-inflammatory

Metabolic ▸ Glucose metabolism ▸ Antidiabetic

Standard StatusStandard

Sequence Length16 amino acids

Chemical FormulaC62H92N20O21S

DescriptionStandard

        GEHGGAGMGGGQFQPV
    

Molecular Weight1485.58 Da

Isoelectric Point (pI)5.24

Net Charge (pH 7.0)-1.15

Net Charge (pH 7.4) -1.40

Charge Density (pH 7.0) -0.0719

GRAVY Index-0.46

Hydrophobic Moment 0.18

Boman Index0.26

Instability Index30.66

Aliphatic Index 24.38

Aromaticity 0.0625

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 643.19

LogP -9.37

H-bond Donors 20.0

H-bond Acceptors 22.0

Rotatable Bonds 47.0

Heavy Atoms 104.0

Ring Count 3.0

Amide Bonds 17.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0016843 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630.0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Anti-inflammatory COX-1 Inhibitory

TargetCyclooxygenase-1 (COX-1)

Activity8.0 μg/mL

MethodIC50

PaperZ?otek U., Jakubczyk A., Rybczy¨½ska-Tkaczyk K., ?wiek P., Baraniak B., Lewicki S.. Characteristics of new peptides GQLGEHGGAGMG, GEHGGAGMGGGQFQPV, EQGFLPGPEESGR, RLARAGLAQ, YGNPVGGVGH, and GNPVGGVGHGTTGT as inhibitors of enzymes involved in metabolic syndrome and antimicrobial potential. Molecules, 25, 2492, 2020. PMID32471271 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32471271/

RECORD: Rec_0054392 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630.0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Anti-inflammatory COX-2 Inhibitory

TargetCyclooxygenase-2 (COX-2)

Activity30.18 μg/mL

MethodIC50

PaperZ?otek U., Jakubczyk A., Rybczy¨½ska-Tkaczyk K., ?wiek P., Baraniak B., Lewicki S.. Characteristics of new peptides GQLGEHGGAGMG, GEHGGAGMGGGQFQPV, EQGFLPGPEESGR, RLARAGLAQ, YGNPVGGVGH, and GNPVGGVGHGTTGT as inhibitors of enzymes involved in metabolic syndrome and antimicrobial potential. Molecules, 25, 2492, 2020. PMID32471271 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32471271/

RECORD: Rec_0107907 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630.0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Anti-inflammatory Lipoxygenase Inhibitory

TargetLipoxygenase

Activity68.48 μg/mL

MethodIC50

PaperZ?otek U., Jakubczyk A., Rybczy¨½ska-Tkaczyk K., ?wiek P., Baraniak B., Lewicki S.. Characteristics of new peptides GQLGEHGGAGMG, GEHGGAGMGGGQFQPV, EQGFLPGPEESGR, RLARAGLAQ, YGNPVGGVGH, and GNPVGGVGHGTTGT as inhibitors of enzymes involved in metabolic syndrome and antimicrobial potential. Molecules, 25, 2492, 2020. PMID32471271 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32471271/

RECORD: Rec_0253829 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630.0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Metabolic Syndrome Pancreatic lipase inhibitory

TargetPancreatic lipase

Activity41.97 μg/mL

MethodIC50

PaperZ?otek U., Jakubczyk A., Rybczy¨½ska-Tkaczyk K., ?wiek P., Baraniak B., Lewicki S.. Characteristics of new peptides GQLGEHGGAGMG, GEHGGAGMGGGQFQPV, EQGFLPGPEESGR, RLARAGLAQ, YGNPVGGVGH, and GNPVGGVGHGTTGT as inhibitors of enzymes involved in metabolic syndrome and antimicrobial potential. Molecules, 25, 2492, 2020. PMID32471271 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32471271/

RECORD: Rec_0324330 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630.0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antihypertensive ACE inhibitory

TargetAngiotensin-converting enzyme I (ACE-I)

Activity490.55 μg/mL

MethodIC50

PaperZ?otek U., Jakubczyk A., Rybczy¨½ska-Tkaczyk K., ?wiek P., Baraniak B., Lewicki S.. Characteristics of new peptides GQLGEHGGAGMG, GEHGGAGMGGGQFQPV, EQGFLPGPEESGR, RLARAGLAQ, YGNPVGGVGH, and GNPVGGVGHGTTGT as inhibitors of enzymes involved in metabolic syndrome and antimicrobial potential. Molecules, 25, 2492, 2020. PMID32471271 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32471271/

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