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MYP_111917
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Basic Information
dCATH 16 (modified from dCATH)
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
16 amino acids
C95H159N29O19
Standard
Sequence
QLVPLAIKIYRAWKRR
Physicochemical Analysis
2011.46 Da
11.73
4.76
4.55
0.2973
-0.26
0.75
-0.19
56.41
128.12
0.1250
6990.00
6990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
807.88
-2.96
30.0
24.0
66.0
143.0
4.0
16.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0020195 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative Anti-Gram-positive Hemolytic
PaperAntimicrobial and anti-inflammatory activities of short dodecapeptides derived from duck cathelicidin: Plausible mechanism of bactericidal action and endotoxin neutralization PMID32698035 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32698035/
RECORD: Rec_0027442 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Salmonella typhimurium C77-31
4 μM
MIC
Paper鸭抗菌肽Cathelicidin的衍生物设计及抑菌机制研究; Design of derivatives of duck antimicrobial peptide Cathelicidin and antibacterial mechanism. [J].东北农业大学学报,2017,48(03):40-47. DOI:10.19720/j.cnki.issn.1005-9369.2017.03.006. Evidence URLhttps://dramp.cpu-bioinfor.org/browse/All_Information.php?dataset=General&id=DRAMP37253
RECORD: Rec_0046136 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus epidermidis ATCC 12228
4 μM
MIC
Paper鸭抗菌肽Cathelicidin的衍生物设计及抑菌机制研究; Design of derivatives of duck antimicrobial peptide Cathelicidin and antibacterial mechanism. [J].东北农业大学学报,2017,48(03):40-47. DOI:10.19720/j.cnki.issn.1005-9369.2017.03.006. Evidence URLhttps://dramp.cpu-bioinfor.org/browse/All_Information.php?dataset=General&id=DRAMP37253
RECORD: Rec_0077980 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative Anti-Gram-positive
Resistant Gram-positive bacteria: MRSA CCARM 3089
32 μM
MIC
PaperAntimicrobial and anti-inflammatory activities of short dodecapeptides derived from duck cathelicidin: Plausible mechanism of bactericidal action and endotoxin neutralization PMID32698035 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32698035/
RECORD: Rec_0104881 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Enterococcus faecalis ATCC 29212
4 μM
MIC
Paper鸭抗菌肽Cathelicidin的衍生物设计及抑菌机制研究; Design of derivatives of duck antimicrobial peptide Cathelicidin and antibacterial mechanism. [J].东北农业大学学报,2017,48(03):40-47. DOI:10.19720/j.cnki.issn.1005-9369.2017.03.006. Evidence URLhttps://dramp.cpu-bioinfor.org/browse/All_Information.php?dataset=General&id=DRAMP37253
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