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MYP_111896
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Basic Information
Defensin-derived D-Peptide D
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antiparasitic ▸ Antiprotozoal
Antiparasitic ▸ Antiprotozoal ▸ Anti-Trypanosoma
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
9 amino acids
C50H97N21O10
Standard
Sequence
RLLLRIGRR
Physicochemical Analysis
1152.44 Da
12.00
3.76
3.56
0.4178
-0.28
1.08
-0.56
93.93
173.33
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
543.72
-3.85
22.0
14.0
41.0
81.0
0.0
8.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0155402 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
synthetic linear peptide [Linear]
all-D amino-acid peptide [D]
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal
Mouse myeloma P3-X63-Ag8.653
52
IC50
PMID19584534;15003352;19154767 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19584534/
RECORD: Rec_0199417 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
synthetic linear peptide [Linear]
all-D amino-acid peptide [D]
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal
Staphylococcus aureus ATCC 6538P
1 μg/mL
MIC
PMID19584534;15003352;19154767 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19584534/
RECORD: Rec_0215162 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
synthetic linear peptide [Linear]
all-D amino-acid peptide [D]
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal
Trypanosoma brucei brucei GUT Tat3.1
325
MIC
PMID19584534;15003352;19154767 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19584534/
RECORD: Rec_0215475 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D or modified amino-acid peptide [Mixed]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PMID19154767 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19154767/
RECORD: Rec_0221752 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
synthetic linear peptide [Linear]
all-D amino-acid peptide [D]
Bio-Activity Profile
Anticancer Cytotoxic
Human cervical carcinoma HeLa
150
IC50
PMID19584534;15003352;19154767 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19584534/
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