‹ ›
MYP_111896
← PREVIOUS NEXT → BACK
Basic Information
Defensin-derived D-Peptide D
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antiparasitic ▸ Antiprotozoal
Antiparasitic ▸ Antiprotozoal ▸ Anti-Trypanosoma
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
9 amino acids
C50H97N21O10
Standard
Sequence
RLLLRIGRR
Physicochemical Analysis
1152.44 Da
12.00
3.76
3.56
0.4178
-0.28
1.08
-0.56
93.93
173.33
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
543.72
-3.85
22.0
14.0
41.0
81.0
0.0
8.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0018682 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
synthetic linear peptide [Linear]
all-D amino-acid peptide [D]
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal
Escherichia coli JM109
2 μg/mL
MIC
PMID19584534;15003352;19154767 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19584534/
RECORD: Rec_0019718 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D or modified amino-acid peptide [Mixed]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PMID19154767 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19154767/
RECORD: Rec_0046079 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
synthetic linear peptide [Linear]
all-D amino-acid peptide [D]
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal
African green monkey kidney cancer Cos-1
426
IC50
PMID19584534;15003352;19154767 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19584534/
RECORD: Rec_0075023 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
synthetic linear peptide [Linear]
all-D amino-acid peptide [D]
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal
Staphylococcus aureus KO-4
20 μg/mL
MIC
PMID19584534;15003352;19154767 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19584534/
RECORD: Rec_0127696 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
synthetic linear peptide [Linear]
all-D amino-acid peptide [D]
Bio-Activity Profile
Anticancer Cytotoxic
Human lung cancer VA-13
640 μM
IC50
PMID19584534;15003352;19154767 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19584534/
1 2 3 ... 5 NEXT LAST
Showing 5 records on this page · Page 1 of 5