Peptide Database

Peptide NameProtein synthesis inhibitor I (EC 3.2.2.22) (Ribosome-inactivating protein I) (rRNA N-glycosidase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antifungal

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme modulation ▸ Enzyme inhibition ▸ Protein Synthesis Inhibitor

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length281 amino acids

Chemical FormulaC1352H2158N374O385S5

DescriptionStandard

        MAAKMAKNVDKPLFTATFNVQASSADYATFIAGIRNKLRNPAHFSHNRPVLPPVEPNVPPSRWFHVVLKASPTSAGLTLAIRADNIYLEGFKSSDGTWWELTPGLIPGATYVGFGGTYRDLLGDTDKLTNVALGRQQLADAVTALHGRTKADKPSGPKQQQAREAVTTLLLMVNEATRFQTVSGFVAGLLHPKAVEKKSGKIGNEMKAQVNGWQDLSAALLKTDVKPPPGKSPAKFAPIEKMGVRTAVQAANTLGILLFVEVPGGLTVAKALELFHASGGK
    

Molecular Weight29972.20 Da

Isoelectric Point (pI)9.86

Net Charge (pH 7.0)12.04

Net Charge (pH 7.4) 11.46

Charge Density (pH 7.0) 0.0428

GRAVY Index-0.13

Hydrophobic Moment 0.64

Boman Index0.08

Instability Index32.27

Aliphatic Index 86.51

Aromaticity 0.0712

Extinction Coeff. Reduced 27960.00

Extinction Coeff. Oxidized 27960.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0388597 VERIFIED: YES

Provenance & Taxonomy

OrganismHordeum vulgare [Plant]

FamilyRibosome-inactivating protein; Type 1 RIP subfamily

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Hydrolase Protein Synthesis Inhibitor Toxin Non-hemolytic