Peptide Database

Peptide NameCYO11_VIOOD

Function Ontology

Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Neurological / Signaling ▸ Signaling peptide

Other / Curated residual function label ▸ Generic enzyme inhibition annotation

Standard StatusStandard

Sequence Length118 amino acids

Chemical FormulaC549H895N139O165S10

DescriptionStandard

        AVVGCSCKSKVCYKNSLADEQAISALTGKTIISNPVLEEALLTHSNSINALGGTLPCGESCVWIPCISMEMKNMVVGLFLIAAFALPALATSFEKDFITHETVQAILKKVGPSSNGML
    

Molecular Weight12403.46 Da

Isoelectric Point (pI)6.10

Net Charge (pH 7.0)-1.08

Net Charge (pH 7.4) -1.48

Charge Density (pH 7.0) -0.0091

GRAVY Index0.49

Hydrophobic Moment 0.55

Boman Index0.25

Instability Index21.79

Aliphatic Index 105.00

Aromaticity 0.0508

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4790.40

LogP -47.58

H-bond Donors 168.0

H-bond Acceptors 176.0

Rotatable Bonds 411.0

Heavy Atoms 863.0

Ring Count 14.0

Amide Bonds 125.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0106831 VERIFIED: YES

Provenance & Taxonomy

OrganismViola odorata [Plant]

FamilyCyclotide

Tax ID97441

Structure & Mods

Confighead-to-tail cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond reported, sites not specified

Bio-Activity Profile

Function

Signaling Enzyme inhibitory ACE inhibitory Antihypertensive

TargetAngiotensin-converting enzyme