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MYP_111662
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Basic Information
ChaC2
Antimicrobial
Standard
30 amino acids
C132H213N37O39S6
Standard
Sequence
GIPCGESCVWIPCISGAIGCSCKSKVCYRN
Physicochemical Analysis
3134.72 Da
8.33
1.70
1.40
0.0567
0.46
0.29
0.18
15.83
74.67
0.0667
6990.00
7365.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1200.91
-14.01
48.0
47.0
98.0
214.0
5.0
30.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0211213 VERIFIED: YES
Provenance & Taxonomy
Viola baoshanensis [Plant]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0224442 VERIFIED: YES
Provenance & Taxonomy
Viola japonica [Plant]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
E-coli
>21.6 μM
MIC
PaperCharacterization and evaluation of cytotoxic and antimicrobial activities of cyclotides from Viola japonica.
RECORD: Rec_0235694 VERIFIED: YES
Provenance & Taxonomy
Viola japonica [Plant]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Bacillus subtilis
5.4 μM
MIC
PaperCharacterization and evaluation of cytotoxic and antimicrobial activities of cyclotides from Viola japonica.
RECORD: Rec_0286574 VERIFIED: YES
Provenance & Taxonomy
Viola tricolor [Plant],Viola baoshanensis [Plant],Viola philippica [Plant]
Cyclotide
214053;349688;39648
Structure & Mods
head-to-tail cyclic peptide scaffold [Cyclic]
canonical L-amino-acid peptide [L]
Cysteine-rich scaffold consistent with multiple disulfide bonds in the annotated family
Bio-Activity Profile
Antimicrobial
PaperIdentification of two suites of cyclotide precursor genes from metallophyte Viola baoshanensis: cDNA sequence variation, alternative RNA splicing and potential cyclotide diversity | Peptidomics of Circular Cysteine-Rich Plant Peptides: Analysis of the Diversity of Cyclotides from Viola tricolor by Transcriptome and Proteome Mining Evidence URLhttps://www.uniprot.org/uniprotkb/B5B3Y8/entry
RECORD: Rec_0314190 VERIFIED: YES
Provenance & Taxonomy
Viola japonica [Plant]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Acinetobacter baumannii
10.8 μM
MIC
PaperCharacterization and evaluation of cytotoxic and antimicrobial activities of cyclotides from Viola japonica.
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