‹ ›
MYP_111662
← PREVIOUS NEXT → BACK
Basic Information
ChaC2
Antimicrobial
Standard
30 amino acids
C132H213N37O39S6
Standard
Sequence
GIPCGESCVWIPCISGAIGCSCKSKVCYRN
Physicochemical Analysis
3134.72 Da
8.33
1.70
1.40
0.0567
0.46
0.29
0.18
15.83
74.67
0.0667
6990.00
7365.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1200.91
-14.01
48.0
47.0
98.0
214.0
5.0
30.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0211213 VERIFIED: YES
Provenance & Taxonomy
Viola baoshanensis [Plant]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli TOP10
3.76 ODID
Mex pooled growth assay (ODID at 4.5 h; Wald adjusted p-value)
PaperKoch P et al. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. DOI:10.1038/s41598-022-07755-7. PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0224442 VERIFIED: YES
Provenance & Taxonomy
Viola japonica [Plant]
Structure & Mods
head-to-tail cyclic cyclotide scaffold [Cyclic]
canonical L-amino-acid peptide [L]
Disulfide bond(s) reported, sites unresolved
Bio-Activity Profile
Antimicrobial
Escherichia coli
>21.6 μM
MIC
PaperCharacterization and evaluation of cytotoxic and antimicrobial activities of cyclotides from Viola japonica.
RECORD: Rec_0235694 VERIFIED: YES
Provenance & Taxonomy
Viola japonica [Plant]
Structure & Mods
head-to-tail cyclic cyclotide scaffold [Cyclic]
canonical L-amino-acid peptide [L]
Disulfide bond(s) reported, sites unresolved
Bio-Activity Profile
Antimicrobial
Bacillus subtilis
5.4 μM
MIC
PaperCharacterization and evaluation of cytotoxic and antimicrobial activities of cyclotides from Viola japonica.
RECORD: Rec_0286574 VERIFIED: NO
Provenance & Taxonomy
Viola tricolor [Plant],Viola baoshanensis [Plant],Viola philippica [Plant]
Cyclotide
214053;349688;39648
Structure & Mods
head-to-tail cyclic cyclotide scaffold [Cyclic]
canonical L-amino-acid peptide [L]
Disulfide bond(s) reported, sites unresolved
Bio-Activity Profile
Antimicrobial
PaperIdentification of two suites of cyclotide precursor genes from metallophyte Viola baoshanensis: cDNA sequence variation, alternative RNA splicing and potential cyclotide diversity | Peptidomics of Circular Cysteine-Rich Plant Peptides: Analysis of the Diversity of Cyclotides from Viola tricolor by Transcriptome and Proteome Mining Evidence URLhttps://www.uniprot.org/uniprotkb/B5B3Y8/entry
RECORD: Rec_0314190 VERIFIED: YES
Provenance & Taxonomy
Viola japonica [Plant]
Structure & Mods
head-to-tail cyclic cyclotide scaffold [Cyclic]
canonical L-amino-acid peptide [L]
Disulfide bond(s) reported, sites unresolved
Bio-Activity Profile
Antimicrobial
Acinetobacter baumannii
10.8 μM
MIC
PaperCharacterization and evaluation of cytotoxic and antimicrobial activities of cyclotides from Viola japonica.
1 2 NEXT LAST
Showing 5 records · Page 1 of 2