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MYP_111550
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Basic Information
Ranatuerin-1T
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antimicrobial ▸ Antifungal ▸ Anti-Candida
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
33 amino acids
C147H260N42O43S3
Standard
Sequence
GLLSGLKKVGKHVAKNVAVSLMDSLKCKISGDC
Physicochemical Analysis
3400.09 Da
9.51
3.82
3.53
0.1159
0.27
0.72
0.08
0.10
112.12
0.0000
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1377.93
-14.48
50.0
51.0
122.0
235.0
1.0
33.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0172412 VERIFIED: YES
Provenance & Taxonomy
European common [Animal]
Ranatuerin
33208
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
27-33
Bio-Activity Profile
Antimicrobial
PMID10651828 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10651828/
RECORD: Rec_0182418 VERIFIED: YES
Provenance & Taxonomy
Rana temporaria [Animal]
Brevinin
8407
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
27-33
Disulfide bridge: C27,C33
Bio-Activity Profile
Antimicrobial
Staphylococcus aureus
120 μM
MIC
PaperRanatuerin 1T: an antimicrobial peptide isolated from the skin of the frog, Rana temporaria.
RECORD: Rec_0216542 VERIFIED: YES
Provenance & Taxonomy
Rana temporaria [Animal]
Ranatuerin
Structure & Mods
Linear peptide with a single intramolecular disulfide-stabilized loop [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
27-33
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus aureus
120.0 μM
MIC
PaperJ. Goraya et al. / Peptides 20 (1999) 159-163. Ranatuerin 1T: an antimicrobial peptide isolated from the skin of the frog, Rana temporaria Evidence URLhttps://www.uniprot.org/uniprotkb/P82740/entry
RECORD: Rec_0220651 VERIFIED: NO
Provenance & Taxonomy
Rana temporaria [Animal]
Brevinin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
27-33
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0274121 VERIFIED: YES
Provenance & Taxonomy
Rana temporaria [Animal]
Ranatuerin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
PMID10422869 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10422869/
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