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MYP_111550
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Basic Information
Ranatuerin-1T
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antimicrobial ▸ Antifungal ▸ Anti-Candida
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
33 amino acids
C147H260N42O43S3
Standard
Sequence
GLLSGLKKVGKHVAKNVAVSLMDSLKCKISGDC
Physicochemical Analysis
3400.09 Da
9.51
3.82
3.53
0.1159
0.27
0.72
0.08
0.10
112.12
0.0000
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1377.93
-14.48
50.0
51.0
122.0
235.0
1.0
33.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0029095 VERIFIED: YES
Provenance & Taxonomy
Rana temporaria [Animal]
Ranatuerin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli
PMID10422869 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10422869/
RECORD: Rec_0033628 VERIFIED: YES
Provenance & Taxonomy
Rana temporaria [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anti-Candida Anti-Gram-positive Non-hemolytic
Staphylococcus aureus
PMID10333736;10422869;34235566 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10333736/
RECORD: Rec_0105729 VERIFIED: YES
Provenance & Taxonomy
Rana temporaria [Plant]
Brevinin
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
PaperPubMed PMID: 10422869 | PubMed PMID: 10333736 PMID10422869;10333736 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10422869/
RECORD: Rec_0109223 VERIFIED: YES
Provenance & Taxonomy
Rana temporaria [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0160509 VERIFIED: NO
Provenance & Taxonomy
Rana temporaria [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PaperPatent US 7862826 B2 Evidence URLhttps://patents.google.com/patent/US7862826B2/en PatentUS 7862826 B2
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