Peptide Database

Peptide NameAVIToxin-VAR2

Function Ontology

Regulatory peptide ▸ Biological modulation

Standard StatusStandard

Sequence Length85 amino acids

Chemical FormulaC396H630N116O115S11

DescriptionStandard

        AVITGACDKDLQCGEGMCCAVSLWIRSIRICTPLGSSGEDCHPLSHKVPFDGQRKHHTCPCLPNLVCGQTSPGKHKCLPEFKNVF
    

Molecular Weight9208.66 Da

Isoelectric Point (pI)8.13

Net Charge (pH 7.0)2.14

Net Charge (pH 7.4) 1.54

Charge Density (pH 7.0) 0.0252

GRAVY Index-0.14

Hydrophobic Moment 0.61

Boman Index0.04

Instability Index59.87

Aliphatic Index 71.06

Aromaticity 0.0471

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 6125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3626.05

LogP -40.02

H-bond Donors 132.0

H-bond Acceptors 133.0

Rotatable Bonds 296.0

Heavy Atoms 638.0

Ring Count 17.0

Amide Bonds 89.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0112445 VERIFIED: YES

Provenance & Taxonomy

OrganismVaranus varius [Animal]

FamilyAVIToxin-VAR2

Tax ID8559

Structure & Mods

Configlinear peptide with reported disulfide constraint [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide7-19; 13-31; 18-59; 41-67; 61-77

Bio-Activity Profile

Function

Receptor modulation

Targetcontracts gastrointestinal (GI) smooth muscle

Half-LifeMammalian: 4.4 hour; Yeast: >20 hour; E. coli: >10 hour