Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length73 amino acids

Chemical FormulaC369H590N106O100S8

DescriptionStandard

        MRIAVPLFTIFFFMSQVLPARGKFKEICERPNGSCRDFCLETEIHVGRCLNSRPCCLPLGHQPRIESTTPKKD
    

Molecular Weight8367.80 Da

Isoelectric Point (pI)8.91

Net Charge (pH 7.0)3.63

Net Charge (pH 7.4) 3.21

Charge Density (pH 7.0) 0.0497

GRAVY Index-0.19

Hydrophobic Moment 0.48

Boman Index-0.05

Instability Index57.50

Aliphatic Index 73.42

Aromaticity 0.0822

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 375.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3287.03

LogP -30.23

H-bond Donors 119.0

H-bond Acceptors 114.0

Rotatable Bonds 272.0

Heavy Atoms 583.0

Ring Count 15.0

Amide Bonds 76.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0081996 VERIFIED: NO

Provenance & Taxonomy

OrganismNomascus leucogenys [Bacterium]

FamilyDefensin

Tax ID61853

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence