Peptide Database

Peptide NameCircular bacteriocin; circularin A uberolysin family

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length71 amino acids

Chemical FormulaC329H540N82O94S3

DescriptionStandard

        MGEVLDLVSTMNISWQSASKVIDAVNAGASIWGIVSIIVAGGGILGMGYAALALLVKKKVKDLGETAAIAW
    

Molecular Weight7244.49 Da

Isoelectric Point (pI)6.00

Net Charge (pH 7.0)-0.50

Net Charge (pH 7.4) -0.73

Charge Density (pH 7.0) -0.0070

GRAVY Index0.85

Hydrophobic Moment 0.57

Boman Index0.39

Instability Index17.80

Aliphatic Index 130.56

Aromaticity 0.0563

Extinction Coeff. Reduced 17990.00

Extinction Coeff. Oxidized 17990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2775.63

LogP -21.91

H-bond Donors 97.0

H-bond Acceptors 97.0

Rotatable Bonds 243.0

Heavy Atoms 508.0

Ring Count 7.0

Amide Bonds 73.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0085438 VERIFIED: NO

Provenance & Taxonomy

OrganismPaenibacillus larvae subsp. larvae [Bacterium]

FamilyCircular bacteriocin

Structure & Mods

Confighead-to-tail cyclic bacteriocin scaffold [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Bacteriocin Non-hemolytic Non-ribosomal

RECORD: Rec_0331723 VERIFIED: NO

Provenance & Taxonomy

OrganismPaenibacillus larvae subsp. larvae DSM 25719 [Bacterium]

FamilyBacteriocin

Tax ID697286

Structure & Mods

Confighead-to-tail cyclic peptide [Cyclic]

Chiralitynoncanonical stereochemical modification [Modified]

Other ModsCyclized peptide scaffold annotation

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Non-hemolytic Non-ribosomal