Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length91 amino acids

Chemical FormulaC457H721N123O142S11

DescriptionStandard

        MPLSMIICTKRFEKLYSEIHNSSTISEKAEYSTKENKAARIKEHYDVFDPWKACVKLNGQCKNQCGENEFKMSYCARPETLCCLKECDPVE
    

Molecular Weight10563.07 Da

Isoelectric Point (pI)6.71

Net Charge (pH 7.0)-0.38

Net Charge (pH 7.4) -0.86

Charge Density (pH 7.0) -0.0042

GRAVY Index-0.67

Hydrophobic Moment 0.65

Boman Index-0.14

Instability Index61.50

Aliphatic Index 57.91

Aromaticity 0.0879

Extinction Coeff. Reduced 11460.00

Extinction Coeff. Oxidized 11960.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4319.51

LogP -42.76

H-bond Donors 155.0

H-bond Acceptors 155.0

Rotatable Bonds 359.0

Heavy Atoms 733.0

Ring Count 15.0

Amide Bonds 97.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0124857 VERIFIED: NO

Provenance & Taxonomy

OrganismFelis catus [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence

RECORD: Rec_0291629 VERIFIED: NO