Peptide Database

Peptide NameCath-B

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Standard StatusStandard

Sequence Length34 amino acids

Chemical FormulaC203H345N59O39

DescriptionStandard

        KRFKKFFRKLKKSVKKRKKEFKKKPRVIGVSIPF
    

Molecular Weight4236.28 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)15.75

Net Charge (pH 7.4) 15.53

Charge Density (pH 7.0) 0.4632

GRAVY Index-1.12

Hydrophobic Moment 0.90

Boman Index-0.50

Instability Index14.58

Aliphatic Index 60.00

Aromaticity 0.1471

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1669.66

LogP -9.06

H-bond Donors 61.0

H-bond Acceptors 55.0

Rotatable Bonds 157.0

Heavy Atoms 301.0

Ring Count 7.0

Amide Bonds 33.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0111118 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyCathelicidin

Tax ID32630.0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetMRSA PS-131

Activity64 μg/mL

MethodMIC

RECORD: Rec_0131909 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyCathelicidin

Tax ID32630.0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetMRSA PS-50

Activity128 μg/mL

MethodMIC

RECORD: Rec_0149016 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetMRSA PS-162

Activity256 μg/mL

MethodMIC

PaperThe antimicrobial potential of a new derivative of cathelicidin from Bungarus fasciatus against methicillin-resistant Staphylococcus aureus. J Microbiol. 2018 Feb;56(2):128-137. doi: 10.1007/s12275-018-7444-5. PMID: 29392557. PMID29392557 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29392557/

RECORD: Rec_0161909 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetGram-negative bacteria

PaperThe antimicrobial potential of a new derivative of cathelicidin from Bungarus fasciatus against methicillin-resistant Staphylococcus aureus. J Microbiol. 2018 Feb;56(2):128-137. doi: 10.1007/s12275-018-7444-5. PMID: 29392557. PMID29392557 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29392557/

RECORD: Rec_0256409 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyCathelicidin

Tax ID32630.0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetEscherichia coli ATCC 25922

Activity2 μg/mL

MethodMIC

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