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MYP_111454
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Basic Information
Grammistin Gs B (Group II grammistin; soapfish, chordates, animals)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
12 amino acids
C70H108N16O14
Standard
Sequence
IGGIISFFKRLF
Physicochemical Analysis
1397.70 Da
11.00
1.76
1.55
0.1466
1.31
0.64
0.46
27.02
130.00
0.2500
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
491.57
-0.71
18.0
16.0
46.0
100.0
3.0
11.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0214406 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial
Horse erythrocytes
Paperhttps://pubmed.ncbi.nlm.nih.gov/17067722/ PMID17067722 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17067722/
RECORD: Rec_0240752 VERIFIED: YES
Provenance & Taxonomy
Grammistes sexlineatus [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus IAM 1011
6.25 μg/mL
MIC
PMID15777955 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15777955/
RECORD: Rec_0256729 VERIFIED: YES
Provenance & Taxonomy
Grammistes sexlineatus [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Vibrio anguillarum NCIBM 829
6.25 μg/mL
MIC
PMID15777955 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15777955/
RECORD: Rec_0279183 VERIFIED: YES
Provenance & Taxonomy
Grammistes sexlineatus [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
dameselae subsp
PMID15777955 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15777955/
RECORD: Rec_0350672 VERIFIED: NO
Provenance & Taxonomy
Grammistes sexlineatus [Animal]
Grammistin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antibiotic Antimicrobial Cytolytic Hemolytic Non-ribosomal
Qualitative functional evidence
PMID15777955 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15777955/; https://www.uniprot.org/uniprotkb/P69839/entry; https://bblserver.org.in/ampdb/
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