Peptide Database

Peptide NameHepcidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length90 amino acids

Chemical FormulaC431H681N119O124S15

DescriptionStandard

        MKAFSIAVAVTLVLAFICILESSAVPFPEVQELEEAGSNDTPVVAHQEMSMASWMMPNHIRQKRQSHLSMCRYCCNCCKGNKGCGFCCKF
    

Molecular Weight9994.72 Da

Isoelectric Point (pI)7.53

Net Charge (pH 7.0)0.68

Net Charge (pH 7.4) 0.17

Charge Density (pH 7.0) 0.0076

GRAVY Index0.17

Hydrophobic Moment 0.53

Boman Index0.11

Instability Index60.90

Aliphatic Index 70.44

Aromaticity 0.0778

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3864.04

LogP -38.71

H-bond Donors 140.0

H-bond Acceptors 143.0

Rotatable Bonds 329.0

Heavy Atoms 689.0

Ring Count 15.0

Amide Bonds 97.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0293428 VERIFIED: NO

Provenance & Taxonomy

OrganismAlepes djedaba [Bacterium]

FamilyHepcidin

Structure & Mods

Configlinear polypeptide/propeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Non-hemolytic Non-ribosomal