Peptide Database

Peptide NameHepcidin

Function Ontology

—

Standard StatusStandard

Sequence Length21 amino acids

Chemical FormulaC87H134N30O23S9

DescriptionStandard

        GCRFCCGCCPNMHGCGVCCRF
    

Molecular Weight2256.77 Da

Isoelectric Point (pI)8.23

Net Charge (pH 7.0)1.77

Net Charge (pH 7.4) 1.40

Charge Density (pH 7.0) 0.0842

GRAVY Index0.61

Hydrophobic Moment 0.33

Boman Index0.11

Instability Index41.03

Aliphatic Index 13.81

Aromaticity 0.0952

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 832.10

LogP -11.17

H-bond Donors 37.0

H-bond Acceptors 35.0

Rotatable Bonds 68.0

Heavy Atoms 149.0

Ring Count 4.0

Amide Bonds 21.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0116398 VERIFIED: YES

Provenance & Taxonomy

OrganismLeiognathus equulus [Animal]

FamilyHepcidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)