Peptide Database

Peptide NameLantibiotic

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length57 amino acids

Chemical FormulaC281H438N72O92S5

DescriptionStandard

        MENFKVIEDIEVSNLLEEIQEDELNEVLGAKKKSGAVPTVSHDCHMNSWQFIFTCCG
    

Molecular Weight6457.24 Da

Isoelectric Point (pI)4.44

Net Charge (pH 7.0)-7.33

Net Charge (pH 7.4) -7.72

Charge Density (pH 7.0) -0.1287

GRAVY Index-0.22

Hydrophobic Moment 0.56

Boman Index0.06

Instability Index42.51

Aliphatic Index 83.68

Aromaticity 0.0702

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5625.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2651.58

LogP -25.06

H-bond Donors 90.0

H-bond Acceptors 92.0

Rotatable Bonds 220.0

Heavy Atoms 450.0

Ring Count 8.0

Amide Bonds 62.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0117570 VERIFIED: NO

Provenance & Taxonomy

OrganismStaphylococcus epidermidis [Bacterium]

FamilyLantibiotic

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic

TargetGram-positive bacteria