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MYP_111296
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Basic Information
BPC188
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Standard
10 amino acids
C62H111N15O12
Standard
Sequence
LLLKKFKKLQ
Physicochemical Analysis
1258.64 Da
10.48
3.76
3.55
0.3756
-0.11
0.53
-0.14
9.59
156.00
0.1000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
472.39
-0.03
16.0
16.0
48.0
89.0
1.0
10.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0088220 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
side-chain cyclized peptide [Cyclic]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anticancer Cytotoxic
MDA-MB-231 cells
14±0.01 %
Growth inhibition assay
PMID20708052 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20708052/
RECORD: Rec_0210382 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
side-chain cyclized peptide [Cyclic]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Human erythrocytes
87±6.5 %
Hemolysis
PMID20708052 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20708052/
RECORD: Rec_0234157 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
side-chain cyclized peptide [Cyclic]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Erwinia amylovora PMV 6076
25-50 μM
MIC
PMID20708052 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20708052/
RECORD: Rec_0243547 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
side-chain cyclized peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
Plant-pathogenic bacteria; MDA-MB-231 cells; Human erythrocytes
MIC panel; Growth inhibition assay; Hemolysis
PaperAntimicrobial cyclic decapeptides with anticancer activity. Peptides. 2010 Nov;31(11):2017-26. doi: 10.1016/j.peptides.2010.07.027. PMID: 20708052. PMID20708052 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20708052/
RECORD: Rec_0273529 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
side-chain cyclized peptide [Cyclic]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Pseudomonas syringae pv. syringae EPS 94
12.5-25 μM
MIC
PMID20708052 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20708052/
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