Peptide Database

Peptide NameBmKDfsin4-F2S/P5S/F6S analog

Function Ontology

Antimicrobial

Standard StatusStandard

Sequence Length37 amino acids

Chemical FormulaC167H268N62O51S6

DescriptionStandard

        GSGCSSNQGQCHKHCQSIRRRGGYCDGFLKTRCVCYR
    

Molecular Weight4152.69 Da

Isoelectric Point (pI)9.38

Net Charge (pH 7.0)5.87

Net Charge (pH 7.4) 5.47

Charge Density (pH 7.0) 0.1587

GRAVY Index-0.89

Hydrophobic Moment 0.58

Boman Index-0.31

Instability Index61.92

Aliphatic Index 28.92

Aromaticity 0.0811

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1881.09

LogP -27.89

H-bond Donors 75.0

H-bond Acceptors 65.0

Rotatable Bonds 140.0

Heavy Atoms 286.0

Ring Count 5.0

Amide Bonds 40.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0081936 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsAPD analysis reveals that this sequence is similar (91.89%) to BmKDfsin4 C=G: 16%; R: 14%, S: 11%. Chemical modification: 3 disulfide bonds

Bio-Activity Profile

Function

Antimicrobial

TargetStaphylococcus aureus ATCC6538