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MYP_111276
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Basic Information
Lichenicidin
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Standard
32 amino acids
C142H239N37O47S5
Standard
Sequence
TITLSTCAILSKPLGNNGYLCTVTKECMPSCN
Physicochemical Analysis
3376.96 Da
7.57
0.36
0.10
0.0112
0.28
0.31
0.16
64.74
85.31
0.0312
1490.00
1740.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1348.52
-17.29
50.0
53.0
108.0
231.0
3.0
34.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0010861 VERIFIED: YES
Provenance & Taxonomy
Bacillus licheniformis ATCC 14580 or VK 21 [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Streptococcus mutans
PMID19561184 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19561184/
RECORD: Rec_0014029 VERIFIED: YES
Provenance & Taxonomy
Bacillus licheniformis ATCC 14580 or VK 21 [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Lactococcus lactis
PMID19561184 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19561184/
RECORD: Rec_0016279 VERIFIED: YES
Provenance & Taxonomy
Bacillus licheniformis [Bacterium]
Structure & Mods
DNA-encoded linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0037568 VERIFIED: YES
Provenance & Taxonomy
Bacillus licheniformis [Bacterium]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
1-Thr: 2-oxobutanoic acid; 5-Ser: 2,3-didehydroalanine (Ser); 6-Thr: (Z)-2,3-didehydrobutyrine
Bio-Activity Profile
Antimicrobial Host defense
PaperPDB 2KTN structural record; NMR; chain A; residues 2-32
RECORD: Rec_0070267 VERIFIED: YES
Provenance & Taxonomy
Bacillus licheniformis strain DSM 13,ATCC 14580 [Bacterium]
Bacteriocin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID19707558 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19707558/
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