Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length80 amino acids

Chemical FormulaC411H644N112O109S10

DescriptionStandard

        MKILFLFLAILLAMEPVVSGRRYPLPCMGNKGVCRASCKKDEQPYLYCKNYQPCCLQPYMRISLVGGEENSDWARGNRWP
    

Molecular Weight9218.84 Da

Isoelectric Point (pI)9.02

Net Charge (pH 7.0)4.44

Net Charge (pH 7.4) 4.12

Charge Density (pH 7.0) 0.0556

GRAVY Index-0.21

Hydrophobic Moment 0.49

Boman Index-0.00

Instability Index63.15

Aliphatic Index 78.00

Aromaticity 0.1125

Extinction Coeff. Reduced 18450.00

Extinction Coeff. Oxidized 18825.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3541.27

LogP -27.55

H-bond Donors 127.0

H-bond Acceptors 124.0

Rotatable Bonds 297.0

Heavy Atoms 642.0

Ring Count 18.0

Amide Bonds 86.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0420214 VERIFIED: NO

Provenance & Taxonomy

OrganismTrichechus manatus latirostris [Bacterium]

FamilyDefensin

Tax ID127582

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence