Peptide Database

Peptide NameEndolysin (EC 3.2.1.17) (Lysis protein) (Lysozyme) (Muramidase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Glycosidase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length157 amino acids

Chemical FormulaC760H1241N221O227S9

DescriptionStandard

        MEAIKIARAAALAVTMLLGLEAMAPRPYLDIAGVLTDCVGNTKDVSWDKLRTKAECMALLESEVGRRVLDIAKDLPDDNWTINNLAAYTSWHYNVSDVGRGTAYDTSTVRKLIRAGKYEQACYGMGAWNKITVNGKKVESRGLTNRRNKEIAVCLRK
    

Molecular Weight17394.91 Da

Isoelectric Point (pI)9.21

Net Charge (pH 7.0)5.56

Net Charge (pH 7.4) 5.19

Charge Density (pH 7.0) 0.0354

GRAVY Index-0.24

Hydrophobic Moment 0.80

Boman Index-0.04

Instability Index33.84

Aliphatic Index 91.40

Aromaticity 0.0637

Extinction Coeff. Reduced 30940.00

Extinction Coeff. Oxidized 31190.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7291.02

LogP -72.50

H-bond Donors 263.0

H-bond Acceptors 243.0

Rotatable Bonds 587.0

Heavy Atoms 1217.0

Ring Count 18.0

Amide Bonds 166.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0076725 VERIFIED: NO

Provenance & Taxonomy

OrganismAchromobacter phage vB_AxyP_19-32_Axy21 [Virus]

FamilyGlycosyl hydrolase 24

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Glycosidase Hydrolase Cytolytic Non-hemolytic