Peptide Database

Peptide NameEA2x3

Function Ontology

Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide

Delivery / Targeting ▸ Drug delivery vehicle

Standard StatusStandard

Sequence Length23 amino acids

Chemical FormulaC80H145N41O30S3

DescriptionStandard

        ARRRCSGSGSGCGSGSGSCGRRR
    

Molecular Weight2257.46 Da

Isoelectric Point (pI)11.70

Net Charge (pH 7.0)5.77

Net Charge (pH 7.4) 5.53

Charge Density (pH 7.0) 0.2507

GRAVY Index-1.10

Hydrophobic Moment 0.39

Boman Index-0.50

Instability Index123.36

Aliphatic Index 4.35

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1196.30

LogP -25.17

H-bond Donors 51.0

H-bond Acceptors 39.0

Rotatable Bonds 78.0

Heavy Atoms 154.0

Ring Count 0.0

Amide Bonds 22.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0036220 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyEA2x3

Tax ID32630

Structure & Mods

Configcyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermExtended with Alanine and an 6-aminohexanoic acid (Ahx) spacer

C-TermAmidation

Bio-Activity Profile

Function

Cell-penetrating peptide Cargo delivery