Peptide Database

Peptide NameGlia-alpha2 (p61-p71; T70, H71 and E66)

Function Ontology

Immunology ▸ Immunomodulation ▸ Celiac-immunogenic

Standard StatusStandard

Sequence Length11 amino acids

Chemical FormulaC64H88N14O17

DescriptionStandard

        PFPQPELPYTH
    

Molecular Weight1325.47 Da

Isoelectric Point (pI)5.25

Net Charge (pH 7.0)-0.95

Net Charge (pH 7.4) -1.06

Charge Density (pH 7.0) -0.0866

GRAVY Index-1.09

Hydrophobic Moment 0.11

Boman Index0.09

Instability Index104.72

Aliphatic Index 35.45

Aromaticity 0.1818

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 463.49

LogP -2.10

H-bond Donors 14.0

H-bond Acceptors 17.0

Rotatable Bonds 33.0

Heavy Atoms 95.0

Ring Count 7.0

Amide Bonds 11.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0246110 VERIFIED: YES

Provenance & Taxonomy

OrganismTriticum aestivum [Plant]

FamilyGliadin

Tax ID4565

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsDeamidation; Reported substitutions/positions: T70,H71; Reported substitutions/positions: E66

Bio-Activity Profile

Function

Celiac-immunogenic

TargetHuman intestinal T cells / HLA-DQ2

MethodIntestinal T-cell assay