‹ ›
MYP_111121
← PREVIOUS NEXT → BACK
Basic Information
oSFTI
Anticancer
Standard
14 amino acids
C67H108N18O20S2
Standard
Sequence
GRCTKSIPPICYPD
Physicochemical Analysis
1549.81 Da
8.05
0.74
0.51
0.0530
-0.42
0.50
-0.05
47.70
55.71
0.0714
1490.00
1615.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
601.16
-6.01
22.0
23.0
44.0
107.0
4.0
13.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0200550 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
SFTI
32630
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
3-11
Bio-Activity Profile
Anticancer
DU-145
Human Serum: The half-life is found to be 34.5 h
PaperBoy RG, Mier W, Nothelfer EM, Altmann A, Eisenhut M, Kolmar H, Tomaszowski M, Krämer S, Haberkorn U. Sunflower trypsin inhibitor 1 derivatives as molecular scaffolds for the development of novel peptidic radiopharmaceuticals Mol Imaging Biol. 2010 Aug;12(4):377-85 PMID:19937135 https://pubmed.ncbi.nlm.nih.gov/19937135/ PMID19937135 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19937135/
RECORD: Rec_0343910 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
SFTI
32630
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
DOTA(metal chelator)
3-11
Bio-Activity Profile
Anticancer
DU-145
Human Serum: The half-life is found to be 41.7 h
PaperBoy RG, Mier W, Nothelfer EM, Altmann A, Eisenhut M, Kolmar H, Tomaszowski M, Krämer S, Haberkorn U. Sunflower trypsin inhibitor 1 derivatives as molecular scaffolds for the development of novel peptidic radiopharmaceuticals Mol Imaging Biol. 2010 Aug;12(4):377-85 PMID:19937135 https://pubmed.ncbi.nlm.nih.gov/19937135/ PMID19937135 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19937135/
RECORD: Rec_0379420 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
SFTI
32630
Structure & Mods
head-to-tail cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
3-11
Bio-Activity Profile
Anticancer
PC-3
Human Serum: The half-life is found to be 75.8 h
PaperBoy RG, Mier W, Nothelfer EM, Altmann A, Eisenhut M, Kolmar H, Tomaszowski M, Krämer S, Haberkorn U. Sunflower trypsin inhibitor 1 derivatives as molecular scaffolds for the development of novel peptidic radiopharmaceuticals Mol Imaging Biol. 2010 Aug;12(4):377-85 PMID:19937135 https://pubmed.ncbi.nlm.nih.gov/19937135/ PMID19937135 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19937135/
RECORD: Rec_0406641 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
SFTI
32630
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
DOTA(metal chelator)
3-11
Bio-Activity Profile
Anticancer
PC-3
Human Serum: The half-life is found to be 41.7 h
PaperBoy RG, Mier W, Nothelfer EM, Altmann A, Eisenhut M, Kolmar H, Tomaszowski M, Krämer S, Haberkorn U. Sunflower trypsin inhibitor 1 derivatives as molecular scaffolds for the development of novel peptidic radiopharmaceuticals Mol Imaging Biol. 2010 Aug;12(4):377-85 PMID:19937135 https://pubmed.ncbi.nlm.nih.gov/19937135/ PMID19937135 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19937135/