Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length152 amino acids

Chemical FormulaC741H1174N198O237S13

DescriptionStandard

        MLTFIICGLLTRVTKGSFEPQKCWKNNVGHCRRRCLDTERYILLCRNKLSCCISIISHEYTRRPAFPVIHLEDITLDYSDVDSFTGSPVSMLNDLITFDTTKFGETMTPETNTPETTMPPSEATTPETTMPPSETATSETMPPPSQTALTHN
    

Molecular Weight17065.28 Da

Isoelectric Point (pI)5.31

Net Charge (pH 7.0)-5.19

Net Charge (pH 7.4) -5.74

Charge Density (pH 7.0) -0.0341

GRAVY Index-0.37

Hydrophobic Moment 0.60

Boman Index-0.01

Instability Index67.21

Aliphatic Index 66.05

Aromaticity 0.0658

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10345.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6915.49

LogP -78.11

H-bond Donors 246.0

H-bond Acceptors 249.0

Rotatable Bonds 543.0

Heavy Atoms 1189.0

Ring Count 29.0

Amide Bonds 159.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0218370 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyDefensin

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence