Peptide Database

Peptide NameVenom peptide 2b (EpVP2b) (VP2b) (Eumenine mastoparan VP2b)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Anti-Candida

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Standard StatusStandard

Sequence Length63 amino acids

Chemical FormulaC298H468N74O86S

DescriptionStandard

        MRGTSFILFAVVVILGFLHGNAEPLANPEPSANPDPLANPDPLANPEAFDLLGLVKSVVSALG
    

Molecular Weight6495.41 Da

Isoelectric Point (pI)4.29

Net Charge (pH 7.0)-4.40

Net Charge (pH 7.4) -4.68

Charge Density (pH 7.0) -0.0699

GRAVY Index0.49

Hydrophobic Moment 0.43

Boman Index0.31

Instability Index21.04

Aliphatic Index 114.60

Aromaticity 0.0635

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2454.20

LogP -20.86

H-bond Donors 77.0

H-bond Acceptors 84.0

Rotatable Bonds 198.0

Heavy Atoms 459.0

Ring Count 13.0

Amide Bonds 67.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0175452 VERIFIED: YES

Provenance & Taxonomy

OrganismEumenes pomiformis [Animal]

FamilyMCD; Mastoparan subfamily

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Cytolytic Hemolytic

TargetGram-negative and Gram-positive bacteria