Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length114 amino acids

Chemical FormulaC552H877N147O168S4

DescriptionStandard

        PDLSGYEKYGLGNVKYNISRIHVTAVEFPSASISLIPGNGIKLVIGNASLTIDMNWNIRTWMFKDSGRSTVYISKVFVTAIFSTPLDNTGHTAMSLTSCRTTSGDIDIKLNGKS
    

Molecular Weight12389.01 Da

Isoelectric Point (pI)9.20

Net Charge (pH 7.0)3.12

Net Charge (pH 7.4) 2.93

Charge Density (pH 7.0) 0.0274

GRAVY Index-0.02

Hydrophobic Moment 0.53

Boman Index0.11

Instability Index17.94

Aliphatic Index 90.61

Aromaticity 0.0877

Extinction Coeff. Reduced 16960.00

Extinction Coeff. Oxidized 16960.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5059.73

LogP -56.00

H-bond Donors 181.0

H-bond Acceptors 177.0

Rotatable Bonds 408.0

Heavy Atoms 871.0

Ring Count 18.0

Amide Bonds 121.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0187332 VERIFIED: NO

Provenance & Taxonomy

OrganismBurhinus bistriatus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria