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MYP_110946
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Basic Information
Brevinin-2Oa
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Standard
32 amino acids
C146H244N42O39S2
Standard
Sequence
GLFNVFKGLKTAGKHVAGSLLNQLKCKVSGGC
Physicochemical Analysis
3275.89 Da
9.90
4.82
4.53
0.1507
0.25
0.65
0.15
-6.78
94.38
0.0625
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1314.16
-14.21
47.0
47.0
114.0
229.0
3.0
34.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0023826 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
26-32
Bio-Activity Profile
Antimicrobial Antifungal
Escherichia coli
2 μM
MIC
PaperAntimicrobial peptides from the skin of the Japanese mountain brown frog, Rana ornativentris
RECORD: Rec_0085860 VERIFIED: YES
Provenance & Taxonomy
Rana Ornativentris [Animal]
Brevinin
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Staphylococcus aureus
PaperPubMed PMID: 11892844 PMID11892844 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11892844/
RECORD: Rec_0086461 VERIFIED: YES
Provenance & Taxonomy
Rana ornativentris [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0203454 VERIFIED: YES
Provenance & Taxonomy
Rana Ornativentris [Animal]
Brevinin
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Candida albicans
PaperPubMed PMID: 11892844 PMID11892844 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11892844/
RECORD: Rec_0219472 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
26-32
Bio-Activity Profile
Antimicrobial Antifungal
Staphylococcus aureus
10 μM
MIC
PaperAntimicrobial peptides from the skin of the Japanese mountain brown frog, Rana ornativentris
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