Peptide Database

Peptide NameTat-Dex

Function Ontology

Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide

Delivery / Targeting ▸ Drug delivery vehicle

Standard StatusStandard

Sequence Length14 amino acids

Chemical FormulaC79H140N36O18

DescriptionStandard

        GRKKRRQRRRPPQY
    

Molecular Weight1882.19 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)7.76

Net Charge (pH 7.4) 7.55

Charge Density (pH 7.0) 0.5541

GRAVY Index-3.34

Hydrophobic Moment 0.48

Boman Index-1.35

Instability Index204.96

Aliphatic Index 0.00

Aromaticity 0.0714

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 953.89

LogP -11.34

H-bond Donors 36.0

H-bond Acceptors 26.0

Rotatable Bonds 65.0

Heavy Atoms 133.0

Ring Count 3.0

Amide Bonds 15.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0224695 VERIFIED: YES

Provenance & Taxonomy

OrganismHuman immunodeficiency virus 1 [Virus]

FamilyTat

Tax ID11676

Structure & Mods

Configcyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermAmidation

Other ModsDexamethasone

Bio-Activity Profile

Function

Cell-penetrating peptide Cargo delivery