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MYP_110923
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Basic Information
Neuromedin-U-23
Cardiovascular
Hormonal / Endocrine ▸ Hormone peptide
Metabolic ▸ Appetite and feeding regulation ▸ Feeding regulator
Neurological / Signaling ▸ Analgesic/opioid activity ▸ Analgesic
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuromuscular and muscle activity ▸ Myotropic activity
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Neurological / Signaling ▸ Pain modulation ▸ Pronociceptive activity
Neurological / Signaling ▸ Sleep regulation
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Regulatory peptide ▸ Cell-cell communication
Standard
23 amino acids
C124H179N33O32
Standard
Sequence
YKVNEYQGPVAPSGGFFLFRPRN
Physicochemical Analysis
2643.95 Da
9.70
1.76
1.55
0.0765
-0.60
0.33
-0.01
46.82
46.52
0.2174
2980.00
2980.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1054.23
-8.99
35.0
34.0
79.0
189.0
8.0
25.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0039324 VERIFIED: YES
Provenance & Taxonomy
Rattus norvegicus [Animal]
Neuromedin-U
10116
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Analgesic Pronociceptive Hormone Endocrine Neuropeptide Neuromodulator Cardiovascular Metabolic regulation Physiological regulation Myotropic Receptor modulation Sleep regulation Wake regulation Feeding regulator
Mammalian: 2.8 hour; Yeast: 10 min; E. coli: 2 min
PaperSource-linked PubMed record(s) for Neuromedin-U-23 (Rattus norvegicus): PMID 7916966 PMID7916966 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/7916966/
RECORD: Rec_0079615 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 8.7%, T 43.5%, C 47.8% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Cell-Cell Communication
PaperNeuroPedia: neuropeptide database and spectral library PMID21821666 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21821666/
RECORD: Rec_0116802 VERIFIED: YES
Provenance & Taxonomy
Rattus norvegicus [Animal]
Neuromedins
10116
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Neuropeptide Hormone
PMID3411332 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/3411332/
RECORD: Rec_0241938 VERIFIED: NO
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Bio-Activity Profile
-
RECORD: Rec_0259703 VERIFIED: NO
Provenance & Taxonomy
Rattus norvegicus [Animal]
10116
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Neuropeptide
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