Peptide Database

Peptide NameAdipokinetic hormone precursor-related peptide alpha chain

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Metabolic

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length28 amino acids

Chemical FormulaC135H203N37O45S2

DescriptionStandard

        DAGDYGDPYSFLYRLIQAEARKMSGCSN
    

Molecular Weight3128.41 Da

Isoelectric Point (pI)4.68

Net Charge (pH 7.0)-1.25

Net Charge (pH 7.4) -1.47

Charge Density (pH 7.0) -0.0446

GRAVY Index-0.65

Hydrophobic Moment 0.67

Boman Index-0.08

Instability Index27.91

Aliphatic Index 52.50

Aromaticity 0.1429

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1346.81

LogP -15.08

H-bond Donors 48.0

H-bond Acceptors 46.0

Rotatable Bonds 101.0

Heavy Atoms 219.0

Ring Count 5.0

Amide Bonds 29.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0113859 VERIFIED: NO

Provenance & Taxonomy

OrganismSchistocerca nitens [Animal]

FamilyAKH/HRTH/RPCH

Tax ID7011

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide Invertebrate neurohormone Metabolic

RECORD: Rec_0230865 VERIFIED: YES

Provenance & Taxonomy

OrganismSchistocerca nitens [Animal]

FamilyAdipokinetic hormone precursor-related peptide

Tax ID7011

Structure & Mods

Configdisulfide-constrained peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide26-26

Bio-Activity Profile

Function

Hormone Endocrine Neuropeptide Neuromodulator

Half-LifeMammalian: 1.1 hour; Yeast: 3 min; E. coli: >10 hour

RECORD: Rec_0424643 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/