Peptide Database

Peptide NameHuman histatin 9

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Standard StatusStandard

Sequence Length14 amino acids

Chemical FormulaC82H123N33O19

DescriptionStandard

        RKFHEKHHSHRGYR
    

Molecular Weight1875.06 Da

Isoelectric Point (pI)11.00

Net Charge (pH 7.0)4.11

Net Charge (pH 7.4) 3.70

Charge Density (pH 7.0) 0.2935

GRAVY Index-2.66

Hydrophobic Moment 0.40

Boman Index-0.80

Instability Index-14.92

Aliphatic Index 0.00

Aromaticity 0.1429

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 871.84

LogP -8.71

H-bond Donors 33.0

H-bond Acceptors 27.0

Rotatable Bonds 63.0

Heavy Atoms 134.0

Ring Count 6.0

Amide Bonds 13.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0370189 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyHistatin

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal

TargetCandida albicans

Activity39±15.8 μg/mL

MethodLD50

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