Peptide Database

Peptide NameAlpha-defensin 2 (Cryptdin-1) (Defensin-related cryptdin-2)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length93 amino acids

Chemical FormulaC442H728N134O147S9

DescriptionStandard

        MKPLVLLSALVLLSFQVQADPIQNTDEETKTEEQSGEEDQAVSVSFGDREGASLQEESLRDLVCYCRTRGCKRRERMNGTCRKGHLMYTLCCR
    

Molecular Weight10559.90 Da

Isoelectric Point (pI)5.40

Net Charge (pH 7.0)-2.44

Net Charge (pH 7.4) -2.83

Charge Density (pH 7.0) -0.0263

GRAVY Index-0.57

Hydrophobic Moment 0.59

Boman Index-0.19

Instability Index45.53

Aliphatic Index 73.33

Aromaticity 0.0430

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4620.47

LogP -53.96

H-bond Donors 168.0

H-bond Acceptors 155.0

Rotatable Bonds 365.0

Heavy Atoms 732.0

Ring Count 7.0

Amide Bonds 100.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0058564 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyAlpha-defensin; Defensin

Tax ID10090

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defensin Non-hemolytic

TargetNo Target Organism Found