Peptide Database

Peptide NameAlpha-defensin-related sequence 12 (CRS4C5) (Cryptdin-related protein 4C-5) (Defensin-related cryptdin-related sequence 12)

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length91 amino acids

Chemical FormulaC436H702N124O132S11

DescriptionStandard

        MKKLVLLSAFVLLAFQVQADSIQNTDEEIKTEEQPGEENQAVSISFGDPEGYALQDAAIRRARRCPPCPSCLSCPWCPRCLRCPMCKCNPK
    

Molecular Weight10145.70 Da

Isoelectric Point (pI)6.20

Net Charge (pH 7.0)-0.57

Net Charge (pH 7.4) -0.94

Charge Density (pH 7.0) -0.0063

GRAVY Index-0.29

Hydrophobic Moment 0.70

Boman Index-0.06

Instability Index72.08

Aliphatic Index 72.97

Aromaticity 0.0549

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4100.68

LogP -42.80

H-bond Donors 145.0

H-bond Acceptors 143.0

Rotatable Bonds 330.0

Heavy Atoms 703.0

Ring Count 15.0

Amide Bonds 99.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0053132 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyAlpha-defensin; Defensin

Tax ID10090

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic

TargetNo Target Organism Found