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MYP_110775
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Basic Information
D-Cbf-14
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
14 amino acids
C86H151N27O16
Standard
Sequence
RLLRKFFRKLKKSV
Physicochemical Analysis
1819.29 Da
12.00
6.76
6.55
0.4826
-0.62
1.08
-0.51
10.91
104.29
0.1429
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
751.63
-3.72
29.0
23.0
67.0
129.0
2.0
13.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0274777 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
K. pneumonia
32 μg/mL
MIC
PMID26897538;29221882 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26897538/
RECORD: Rec_0291769 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Cryptococcus neoformans 5
16 μg/mL
MIC
PMID26897538;29221882 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26897538/
RECORD: Rec_0292605 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli ATCC 25922
32 μg/mL
MIC
PMID28522372 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28522372/
RECORD: Rec_0305448 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Sheep RBC
512 μg/mL
HC50
PMID26897538;29221882 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26897538/
RECORD: Rec_0326982 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
all-D amino-acid peptide [D]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Cytotoxic
In mice spleen cells, the peptide produced cell viability of 97% at 800 μg/ml
PMID28522372 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28522372/
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