Peptide Database

Peptide NameANP

Function Ontology

Atrial natriuretic peptide

Standard StatusStandard

Sequence Length26 amino acids

Chemical FormulaC120H193N43O37S2

DescriptionStandard

        SLRRSSCFGGRIDRIGAQSGCNSFRY
    

Molecular Weight2894.21 Da

Isoelectric Point (pI)10.66

Net Charge (pH 7.0)3.44

Net Charge (pH 7.4) 3.20

Charge Density (pH 7.0) 0.1323

GRAVY Index-0.57

Hydrophobic Moment 0.64

Boman Index-0.25

Instability Index88.48

Aliphatic Index 48.85

Aromaticity 0.1154

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1615.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1345.18

LogP -19.61

H-bond Donors 53.0

H-bond Acceptors 43.0

Rotatable Bonds 97.0

Heavy Atoms 202.0

Ring Count 3.0

Amide Bonds 27.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0297407 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyNatriuretic peptide

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Atrial natriuretic peptide

MethodRadioimmunoassay

Half-LifeHuman blood plasma, in vitro; 144 s